Hormone Replacement Therapy (HRT) versus Bioidentical Hormone Replacement Therapy (BHRT): Key Points to Understand

Hormone Replacement Therapy (HRT) versus Bioidentical Hormone Replacement Therapy (BHRT): Key Points to Understand

Hormone replacement therapy (HRT) and bioidentical hormone replacement therapy (BHRT) are treatments designed to address hormone imbalances, helping people of all genders manage symptoms related to aging, menopause, or various health conditions.

Traditional HRT often involves synthetic or animal-derived hormones that may not be identical to the body's natural hormones. On the other hand, BHRT, a more recent development, uses plant-derived hormones, typically from sources such as yams or soy, that are chemically identical to those the human body produces.

BHRT has gained popularity due to its "natural" appeal, but it's essential to remember that there is BHRT that is FDA approved and is not FDA approved. FDA-approved BHRT is regulated, while compounded hormone therapy, which lacks support from rigorous research, is not.

Both HRT and BHRT are available in various forms, including oral tablets, topical creams, patches, injections, and vaginal rings. The choice of delivery method depends on factors such as convenience, absorption rates, and specific symptoms being targeted.

While BHRT may help alleviate menopausal symptoms in females, similar to HRT, it could carry the same risks as traditional HRT, including the possibility of blood clots, stroke, breast cancer, and heart disease. The National Academies of Sciences, Engineering, and Medicine (NASEM) guidelines recommend avoiding BHRT for testosterone replacement unless a person has a known allergy or sensitivity to traditional TRT options.

HRT can help protect against long-term risks associated with hormone deficiency, such as osteoporosis and cardiovascular disease. For males, BHRT may provide benefits similar to traditional TRT, helping alleviate symptoms of low testosterone.

It's crucial to discuss the pros and cons of BHRT with a healthcare professional before deciding. A healthcare professional should consider personal health history, symptoms, and risk factors when deciding between BHRT and HRT. The claims that bioidentical hormones are safer or more effective than their synthetic or animal-derived counterparts are minimal or unsupported by evidence.

In conclusion, while both HRT and BHRT can be effective in managing symptoms of hormonal imbalances, they carry different risks and benefits. It's essential to consult with a healthcare professional to determine the best course of treatment for individual needs.

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